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Occupational Medicine 1979;29:142-143
© 1979 Society of Occupational Medicine

research-article

Effects of n-Butyl Glycidyl Ether Exposure*

E. WALLACE, Employment Medical Adviser, Health and Safety Executive

London and South East Region

The first investigations of the toxicity of n-butyl glycidyl ether (BGE) on animals are reported to have been carried out by Hines et al. (1965). They state that, while experimentally it was possible to produce death in rodents by exposure to its vapours, the practical hazard to man from the vapour exposure appears to be relatively slight since, in common with other irritating industrial chemicals, it offers ample warning of its presence. There had been no reports of significant exposure of man to the compound.

In the accident reported here two men were exposed to a spillage of approximately 3.51, one man for one and a half hours and the other for four hours. In spite of the persistent smell, they continued with their work. The symptoms which the men found to be most distressing were those relating to the digestive and nervous systems and not the respiratory tract.

Dr E. Wallace, Employment Medical Adviser, London and South East Region, 1 Long Lane, London, SE1 4PG.


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