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Occupational Medicine 1985;35:107-110
© 1985 Society of Occupational Medicine

research-article

Sixteen Year Follow Up of Workers in an Explosives Factory

R. CRAIG1,0, C.R. GILLIS2, D.J. HOLE2 and G.M. PADDLE3

1 Nobel's Explosives Company
2 Greater Glasgow Health Board
3 Imperial Chemical Industries, Central Medical Group

Nitroglycerine (NG) has been used in the manufacture of explosives for over 100 years and ethylene glycol dinitrate (EGDN), a commonly used synonym being nitroglycol, for over 50 years. The acute effects of exposure to these two substances are well known. The possible long-term effects have been the subject of debate for many years but only recently has a definitive study indicated an excess of deaths from cardiovascular disease and cerebrovascular disease in exposed workers.

A cohort of male employees in an explosives factory was defined, some of whom had had exposure to NG and EGDN. Observance of mortality experience over 16 years revealed an excess of deaths from acute myocardial infarction in the younger group of workers exposed to both substances.

0Requests for reprints should be addressed to: Dr R. Craig, Senior Medical Officer, Nobel's Explosives Company Limited, Nobel House, Stevenston, Ayrshire KA20 3LN, Scotland.


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