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Occupational Medicine 1997;47:473-478
© 1997 Society of Occupational Medicine

research-article

Enzyme exposure, smoking and lung function in employees in the detergent industry over 20 years

M. Cathcart*,, D. Nicholson{dagger}, D. Roberts{ddagger}, M. Bazley{ddagger}, C. Juniper{ddagger}, P. Murray$$$, M. Randell{dagger} and Medical Subcommittee of the UK Soap and Detergent Industry Association

* Albright & Wilson UK Limited PO Box 3, 210-222 Hagley Road West, Oldbury, Warley, West Midlands, UK
{dagger} Procter and Gamble PO Box 1EE, Gosforth, Newcastle upon Tyne, UK
{ddagger} Unilever Plc, Unilever House Blackfriars, London, UK
$$$ Unilever Research and Engineering PO Box 114, 3130 AC, Vlaardingen, Netherlands

This study was undertaken to examine the long term relationship between lung function, smoking and exposure to enzymes in the detergent industry. A total of 731 male workers from five locations in the United Kingdom were subject to respiratory health surveillance including lung function testing over a period of 4–20 years. Exposure groups were defined by job history. Significantly different rates of fall in FEV1 and FVC with time were fourtd by geographical location and by smoking habit, but there were no consistent trends with enzyme exposure.

Keywords      Detergent; detergent industry; enzymes; lung function tests; smoking

Received        7 October 1996
Accepted       12 June 1997

Correspondence and reprint requests to: M. Cathcart, Albright & Wilson UK Limited, PO Box 3, 210-222 Hagley Road West, Oldbury, Warley, West Midlands, UK


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