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Occupational Medicine 2005 55(2):145-148; doi:10.1093/occmed/kqi018
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Occupational Medicine, Vol. 55 No. 2 © Society of Occupational Medicine 2005; all rights reserved

Case Report

Occupational molybdenum exposure and a gouty electrician

Anders I. Seldén1, N. Peter Berg1, Annika Söderbergh2 and Bernt E. O. Bergström1

1 Department of Occupational and Environmental Medicine, Örebro University Hospital, SE-701 85 Örebro, Sweden2 Department of Rheumatology, Örebro University Hospital, SE-701 85 Örebro, Sweden

Background Molybdenum is an essential trace element and a component of xanthine oxidase, which catalyses the formation of urate. The toxicity of molybdenum in humans is considered to be low, but hyperuricaemia and gout-like symptoms have been observed sporadically.

Methods A case of hyperuricaemia and gouty arthritis in a young man with occupational exposure to molybdenum is described. Improvement during an exposure-free period was followed by a relapse after a reconstruction designed to quantify his molybdenum exposure.

Conclusion This case seems to represent the first observation of gout associated with occupational molybdenum exposure, but the association might also be entirely circumstantial.

Keywords      Gout; hyperuricaemia; molybdenum; occupational exposure

Received       17 May 2004
Revised         23 August 2004
Accepted       26 September 2004

* Correspondence to: Dr Anders Seldén, Department of Occupational and Environmental Medicine, Örebro University Hospital, SE-701 85 Örebro, Sweden. Tel: +46 19 602 24 94; fax: +46 19 12 04 04; Email: anders.selden{at}orebroll.se


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