Occupational Medicine Advance Access originally published online on May 21, 2009
Occupational Medicine 2009 59(7):476-482; doi:10.1093/occmed/kqp066
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Current perception threshold and the HAVS Stockholm sensorineural scale
1 Division of Occupational and Environmental Health, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
2 Department of Occupational and Environmental Health, St Michael's Hospital, Toronto, Ontario, Canada
3 Engineering and Control Technology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV, USA
4 Department of Epidemiology, University of Nebraska Medical Center, Omaha, NE, USA
Background It is important to determine which tests of sensorineural dysfunction identify the neurological damage from hand–arm vibration exposure.
Aims To examine the association between the hand–arm vibration syndrome (HAVS) Stockholm sensorineural scale stages and tests of peripheral neurological function including measurement of current perception threshold (CPT) and nerve conduction.
Methods All the subjects were men who were assessed for HAVS with a medical and occupational history and physical examination to determine the Stockholm stage, CPT testing at frequencies of 5, 250 and 2000 Hz for the median and ulnar nerves and measurement of nerve conduction carried out in a blinded fashion.
Results A total of 155 of the 157 recruited subjects agreed to take part in the study, a 99% participation rate. CPT was statistically significantly increased (P < 0.001) in both Stockholm sensorineural Stages 1 and 
2 in comparison to Stage 0 for every frequency and nerve combination. However, CPT could not discriminate well between Stages 1 and 2. There was no association between median or ulnar neuropathy measured by nerve conduction and the Stockholm stages. Polychotomous multinomial logistic regression indicated that the CPT measurements at 2000 Hz, corresponding to damage to large myelinated nerve fibres, were most predictive of both Stockholm Stages 1 and 2 in comparison to Stage 0.
Conclusions Neuropathy measured by nerve conduction was unrelated to the Stockholm scale stages. CPT was increased above Stage 0 but did not distinguish well between the higher stages of the Stockholm scale.
Keywords Current perception threshold; HAVS; Stockholm sensorineural scale; vibration
Correspondence to: Ron House, Department of Occupational and Environmental Health, St Michael's Hospital, 30 Bond Street, Toronto, Ontario M5B 1W8, Canada. Tel: +1 416 864 5074; fax: +1 416 864 5421; e-mail: houser{at}smh.toronto.on.ca