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Occupational Medicine Advance Access published online on August 30, 2007
Occupational Medicine, doi:10.1093/occmed/kqm077
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© The Author 2007. Published by Oxford University Press on behalf of the Society of Occupational Medicine. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Case Report

Hydrazine inhalation hepatotoxicity

Yung Hsiang Kao1, CH Chong2, WT Ng3 and D Lim4

1 Singapore Health Services, 7 Hospital Drive Blk B, #02-15, Singapore 169611, Singapore
2 Republic of Singapore Air Force Medical Service, 492 Airport Road,Singapore 539945, Singapore
3 General Staff Branch, Republic of Singapore Air Force Medical Service, 492 Airport Road, Singapore 539945, Singapore
4 Crew Safety and Flight Environment Branch, Republic of Singapore Air Force Medical Service, 492 Airport Road, Singapore 539945, Singapore

Hydrazine is a hazardous chemical commonly used as a reactant in rocket and jet fuel cells. Animal studies have demonstrated hepatic changes after hydrazine inhalation. Human case reports of hydrazine inhalation hepatotoxicity are rare. We report a case of mild hepatotoxicity following brief hydrazine vapour inhalation in a healthy young man, which resolved completely on expectant management.

Keywords      Hepatotoxicity; hydrazine; inhalation; management; transaminitis

Correspondence to: Yung Hsiang Kao, 135 Countryside Road, Singapore 789856, Singapore. Tel: +65 64674111; e-mail: kaoyh{at}yahoo.com


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